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. 2022 Jan 11;119(3):e2025448119. doi: 10.1073/pnas.2025448119

Table 1.

Mean reduction in reported cases, hospitalization, and reported deaths or mortality from equal-sized HVIs by targeted age group, assuming maximal 15% efficacy for both transmission reduction and clinical effectiveness

HVI initiation month 20+ 40+ 65+
Reported cases Hospitalization Mortality Reported cases Hospitalization Mortality Reported cases Hospitalization Mortality
September 24.1 7.9 7.3 18.9 10.9 12.7 6.8 9.1 13.3
October 24.3 9.0 8.4 18.9 11.3 12.4 6.8 9.0 13.1
November 24.5 12.1 11.8 18.8 12.8 14.1 6.7 9.1 13.2
December 22.6 16.0 16.4 17.0 14.2 15.7 6.0 8.7 12.5
January 15.7 14.4 14.9 11.9 12.2 13.5 4.5 7.4 10.7
February 6.7 7.0 7.4 5.4 6.3 7.0 2.3 4.0 5.7

Percent reduction versus baseline simulation through June 30th, 2021; maximal reduction in each category in bold.