Table 4.
Contribution of discrepant MICs in the production of categorical errors using EUCAST breakpoints for Staphylococcus spp.
| Antimicrobiala | No. of discrepant MICsb | No. of discrepant MICs in the range of the clinical category of |
No. of discrepant MICs producing categorical errorsc |
|||||
|---|---|---|---|---|---|---|---|---|
| S | R | I | Overall errors | VMEs | MEs | mEs | ||
| Daptomycin | 70 | 67 | 3 | 0 | 4/4 | 3/3 | 1/1 | NA |
| Oxacillin | 77 | 67 | 10 | 0 | 14/16 | 10/11 | 4/5 | NA |
| Fosfomycin | 5 | 0 | 5 | 0 | 1/2 | NA | 1/2 | NA |
| Clindamycin | 48 | 0 | 27 | 21 | 3/8 | 0/4 | 3/3 | 0/1 |
| Penicillin G | 39 | 3 | 36 | 0 | 1/3 | 1/2 | NA | 0/1 |
| Tobramycin | 22 | 1 | 21 | 0 | 13/18 | 0/1 | 13/17 | NA |
| Erythromycin | 30 | 23 | 1 | 5 | 6/6 | 2/2 | 1/1 | 3/3 |
| Gentamicin | 26 | 1 | 25 | 0 | 14/14 | NA | 14/14 | NA |
| Amikacin | 7 | 0 | 5 | 2 | 5/21 | NA | 2/2 | 3/19 |
| Linezolid | 26 | 16 | 10 | 0 | 13/13 | 12/12 | 1/1 | NA |
| Fusidic acid | 9 | 1 | 8 | 0 | 1/1 | 1/1 | NA | NA |
| Levofloxacin | 12 | 6 | 6 | 0 | 3/3 | 1/1 | 2/2 | NA |
| Rifampicin | 10 | 2 | 8 | 0 | 1/2 | NA | 1/2 | NA |
| Tetracycline | 7 | 4 | 2 | 1 | 4/5 | 2/2 | 1/1 | 1/2 |
| Cefoxitin | 5 | 5 | 0 | 0 | 2/2 | 2/2 | NA | NA |
NA, not applicable.
a
Antimicrobials for which discrepant MICs did not produce any errors are not shown.
b
MICs >1 dilution from the reference values were considered discrepant.
c
The numerator of the fraction indicates the number of errors produced only by discrepant MICs. The denominator indicates the number of errors produced by discrepant MICs (MICs >1 dilution from the reference values) and non-discrepant MICs (MICs within ±1 dilution from the reference values). Errors produced only by discrepant MICs are in bold.