Table 1.
Characteristics of Transplanted Subjects and Comparators with End-Stage Renal Disease Due to Granulomatosis with Polyangiitis
| Baseline Characteristics | Transplanted | Not Transplanted |
|---|---|---|
| N | 593 | 436 |
| Age at ESRD* (years, mean, SD) | 46.4, 17.4 | 52.6, 15.0 |
| <40 (%) | 32.0 | 18.1 |
| 40–49 (%) | 17.2 | 15.1 |
| 50–59 (%) | 20.4 | 26.2 |
| >=60 (%) | 30.4 | 40.6 |
| Female (%) | 42.7 | 41.7 |
| BMI (kg/m2, mean, SD) | 27.0, 6.4 | 27.7 |
| Race (%) | ||
| White | 85.5 | 79.6 |
| African American | 5.4 | 9.6 |
| Asian | 1.9 | 2.3 |
| Other | 7.3 | 8.5 |
| Hispanic (%) | 13.7 | 16.5 |
| OPTN Region (%) | ||
| 1 (CT, ME, MA, NH, RI, Eastern VT) | 4.9 | 4.6 |
| 2 (DE, DC, MD, NJ, PA, WV, Northern VA) | 9.8 | 10.6 |
| 3 (AL, AR, FL, GA, LA, MS) | 10.8 | 11.9 |
| 4 (OK, TX) | 7.9 | 9.9 |
| 5 (AZ, CA, NV, NM, UT) | 14.8 | 16.1 |
| 6 (AK, HI, ID, MT, OR, WA) | 6.6 | 5.1 |
| 7 (IL, MN, ND, SD, WI) | 11.5 | 9.9 |
| 8 (CO, IA, KA, MO, NE, WY | 9.1 | 6.9 |
| 9 (NY, Western VT) | 3.7 | 5.7 |
| 10 (IN, MI, OH) | 9.8 | 5.5 |
| 11 (KY, NC, SC, TN, VA) | 11.1 | 14.0 |
| Prior Organ Transplant (%) | <11 | <11 |
| Panel Reactive Antibodies (PRA) (mean, SD) | 0.14, 0.30 | 0.17, 0.31 |
| Comorbidities at Waitlisting | ||
| Charlson Comorbidity Index (mean, SD) | 4.2, 3.2 | 4.0, 3.1 |
| Hypertension (%) | 81.8 | 70.4 |
| Diabetes (with or without complications) (%) | 35.2 | 30.3 |
| Dyslipidemia (%) | 56.0 | 43.4 |
| Congestive heart failure (%) | 24.3 | 33.7 |
| Chronic obstructive pulmonary disease (%) | 34.2 | 32.1 |
| Asthma (%) | 23.8 | 23.2 |
| Malignancy (%) | 12.1 | 11.2 |
| No of Hosp in the Six Months Prior to Waitlisting (median, IQR) | 0 [0,0] | 0 [0,0] |
| Time on dialysis prior to waitlisting (mean, SD) | 1.1, 1.5 | 1.4, 2.2 |
| Time from waitlisting to transplantation (mean, SD) | 1.6, 1.6 | — |
| First Modality (%) | ||
| Hemodialysis | 82.3 | 87.6 |
| Peritoneal Dialysis | 17.7 | 12.4 |
| Transplant Type (%) | ||
| Living | 85.3 | 67.7 |
| Deceased | 77.8 | 32.3 |