Impact of vaccination on convalescent plasma neutralizing activity
(A and B) Single measurements (dots) and individual evolution (lines) of the longitudinal analysis for vaccinated non-hospitalized (n = 40) and hospitalized (n = 18) individuals. Blue dots (light or dark) correspond to pre-vaccination measurements. Post-vaccine data are color-coded according to vaccine schedules: BNT162b2 (maroon), mRNA-1273 (red), and AZD1222 (purple). Full symbols indicate full schedule (two doses), while half circles indicate one single dose.
(C) Comparison of pre- and post-vaccination neutralizing antibody titers in both groups. Lower p values indicate paired comparison (Wilcoxon test) of pre- and post-values. Upper p value indicates Mann-Whitney comparison of pre-vaccination between groups. Geometric means of neutralization titer for each group are indicated. Dotted lines indicate the upper and lower limits of detection.