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Treatment with NVP-BEZ235, PP242, and Rapamycin induced cell cycle arrest in RCC cells. (A) UMRC6, (B) 786-0, and (C) UOK121 cells were incubated with indicated concentrations of NVP-BEZ235, PP242, and Rapamycin for 72 h. DMSO-treated cells served as control (0 nM). The proportion of cells in different phases of the cell cycle was determined by flow cytometry.
