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. 2022 Jan 10;8:769555. doi: 10.3389/fnut.2021.769555

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Copyright © 2022 Dai, Lv, Qiao, Wang, Zhou, Bao, Zhang, Fu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative images of renal pathological H&E staining with hyperuricemia (A–G) (original magnification, 400×). (A) Control group; (B) Model group; (C) Benzbromarone group (with hyperuricemia); (D) Allopurinol group (with hyperuricemia); (E) HSCE group; (F) MSCE group; (G) LSCE group; (a) control group; (b) model group; (c) benzbromarone group; (d) allopurinol group; (e) lSCE group; (f) mSCE group; and (g) hSCE group. Circles indicate area of kidney lesions. The histogram represented the evaluation of unilateral kidney weight and displayed with mean ± SD.