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The mutational landscape of two immune subtypes. (A) Three mutation signatures were extracted from two immune subtype and named according to the COSMIC signature. The proportion of each mutation signature, which reflects the likely carcinogenic factors. (B) The relative contribution of three signature in C1 and C2. (C,D) The mutational landscape (C) and frequency (D) of 27 significant mutation genes (SMGs) in two subtypes.
