Pathways and cell population changes of COVID-19
(A) The pathways that show significant differences in all or the majority of the five tissue types are shown, with statistical significance from GSEA testing across five kinds of tissue (colors in legend), including heart (n = 41), kidney (n = 27), liver (n = 40), lung (n = 40), and lymph node (n = 27). The x axis shows the normalized enrichment score for COVID-19-positive versus control, SARS-CoV-2 high or low versus control, and SARS-CoV-2 high versus Low comparisons.
(B) Cellular deconvolution distribution violin plots for the heart, kidney, liver, and lung. SARS-CoV-2 high (red), low (orange), and normal (blue) tissues are shown using a square root scale. The number of biological replicates is the same as in (A).