FIGURE 1.

Schematic diagram of metabolic engineering for the production of mcl-PHA from a mixture of xylose and glucose by the microbial consortium based on the concept of “nutrient supply-detoxification” (Acronyms: X5P, Xylulose 5-phosphate; G3P, Glyceraldehyde-3-phosphate; Acetyl-P, Acetyl Phosphate; G6P, Glucose-6-Phosphate. The red crosses in the biosynthetic pathway indicate the deletion of corresponding genes. The bold green arrows indicate the overexpression of corresponding genes. The related genetic engineering represented by ①, ②, ③, and ④ was completed by (Liu et al., 2020), and the corresponding genetic engineering represented by ⑤ was completed by (Yang et al., 2019). The related genetic engineering represented by ⑥, ⑦, ⑧, ⑨, and ⑩ was conducted in this work).