Figure 4.
Different kinase pathways show distinct mRNA signatures when inhibited
(A and B) Across all models, tyrosine kinase (TK)-targeting drugs performed the best.
(C) Distribution of kinases profiled across the Human Kinome annotated by kinase group.
(D) Correlation of kinase-binding data with transcriptional program.
(E and F) KEGG pathway transformation of kinase space from (C) revealed pathway-specific transcriptional signatures