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. 2022 Jan 10;13:799824. doi: 10.3389/fnagi.2021.799824

Table 2.

The subgroup analysis of studies reporting Mg levels in peripheral blood.

Subgroups n of studies SMD (95% CI) I2 P-value
All studies 18 −0.89 (−1.36, −0.43) 94.4% 0.000
Methods
AAS 4 −2.62 (−4.59, −0.66) 95.5% 0.000
ICP-AES 4 −0.81 (−2.11, 0.49) 97.1% 0.000
Spectrophotometry 5 −1.12 (−2.19, −0.04) 95.2% 0.000
ICP-MS 3 0.09 (−0.13, 0.31) 0.0% 0.881
ISE 1 −0.30 (−0.71, −0.11) - -
- 1 0.14 (−0.20, 0.48) - -
Geographic locations
Asia 11 −1.01 (−1.54, −0.47) 93.1% 0.000
Europe 7 −0.65 (−1.58, 0.28) 96.2% 0.000

ICP-MS, inductively coupled plasma-mass spectrometry; ICP-AES, inductively coupled plasma-atomic emission spectrometry; AAS, atomic absorption spectrometry; ISE, ion-selective electrode.