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. 2022 Jan 10;13:799824. doi: 10.3389/fnagi.2021.799824

Table 3.

The subgroup analysis of studies reporting circulating Mg levels.

Subgroups n of studies SMD (95% CI) I2 P-value
All studies 21 −0.74 (−1.13, −0.35) 93.6% 0.000
Methods
AAS 4 −2.62 (−4.59, −0.66) 95.5% 0.000
ICP-AES 4 −0.81 (−2.11, 0.49) 97.1% 0.000
Spectrophotometry 6 −0.93 (−1.74, −0.11) 94.4% 0.000
ICP-MS 5 0.01 (−0.24, 0.25) 44.4% 0.126
ISE 1 −0.30 (−0.71, −0.11) - -
- 1 0.14 (−0.20, 0.48) - -
Geographic locations
Asia 12 −0.88 (−1.39, −0.37) 92.6% 0.000
Europe 8 −0.61 (−1.36, 0.15) 95.6% 0.000
Africa 1 −0.21 (−0.54, 0.12) - -

ICP-MS, inductively coupled plasma-mass spectrometry; ICP-AES, inductively coupled plasma-atomic emission spectrometry; AAS, atomic absorption spectrometry; ISE, ion-selective electrode.