FIGURE 5.

ICN transection leads to smaller laser-induced CNV lesions. Lesion volumes were measured with SD-OCT at 3, 7, 10, and 14 days after laser treatment (left). Following euthanasia on day 14, volumes were measured ex vivo with confocal microscopy (right). By day 14, animals that underwent ICN transection had statistically smaller lesions than the animals that received sham surgery (n ≥ 44 lesions per group from six animals per group; ***P < 0.001). This was true regardless of whether ICN transection was performed immediately after or 7 days after laser therapy. Error bars represent SEM.