Table 4B.

Luminex results^* stratified for urine recirculation and urine replacement.

	Kidneys with urine recirculation (n = 8)		Kidneys without urine recirculation (n = 4)		p-value***1 h	p-value***6 h
	1 h**	6 h**	1 h**	6 h**
GM-CSF	420.6, 9,993	53.5, 2,300	10,000, 0	12.6, 27.7	0.11	0.21
IFN-γ	10,000, 0	10,000, 9,982	10,000, 0	10,000, 0	>0.9	0.42
IL-10	2,160, 8196	1,890, 3,727	5,023, 9,988	1,214, 3,607	>0.9	>0.9
IL-12p40	10,000, 0	10,000, 7,481	10,000, 0	10,000, 7,499	>0.9	0.83
IL-12p70	10,000, 0	10,000, 0	10,000, 0	10,000, 7,493	>0.9	>0.9
IL-1RA	1,214, 2,229	1,933, 2,710	453.7, 419.7	192.6, 969	0.68	0.26
IL-1α	10,000, 0	10,000, 9,935	5,010, 9,986	10,000, 0	0.09	0.42
IL-1β	5,082, 9,986	113.7, 7,534	10,000, 7,499	1.2, 3	0.67	0.02
IL-2	10,000, 9,998	19.7, 7,518	10,000, 0	5,001, 9,999	0.42	0.53
IL-4	10,000, 0	10,000, 0	10,000, 0	10,000, 0	>0.9	>0.9
IL-6	4,493, 9,040	8,496, 4,829	19.6, 47.7	5,224, 14,384	0.11	0.68
IL-8	66.1, 10,943	16,501, 35,438	23.9, 55.5	17,625, 9,744	0.77	0.89
TNF-α	18.4, 560.8	459.7, 1,277	8.9, 9.4	354.7, 221.3	0.46	0.37

^*Number of cells in pg/ml; overall perfusate volume = 500 ml.

^**Time after start of NMP, values in median and IQR (interquartile range).

^***P-value result of comparison with and without urine recirculation.

GM-CSF, granulocyte-macrophage colony-stimulating factor; IFN, interferon; IL, interleukin; TNF, tumor necrosis factor.