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. 2022 Jan 24;20(1):e07121. doi: 10.2903/j.efsa.2022.7121

Table 1.

Sample size and confidence level (probability to detect animals with clinical signs) achieved in an establishment as a function of the herd size and the target (design) prevalence of animals with clinical signs (1%) and (0.5%), respectively. Sensitivity of the clinical examination Se = 75%

Herd size Example for (design) prevalence of animals with clinical signs 1% Example for (design) prevalence of animals with clinical signs 0.5%
(Design) Prevalence of animals with clinical signs Sample size Confidence level (Design) Prevalence of animals with clinical signs Sample Size Confidence level
10 10%* 10 74% 10%* 10 74%
20 5%* 20 74% 5%* 20 74%
50 2%* 50 75% 2%* 50 75%
100 1% 100 75% 1%* 100 75%
200 1% 200 94% 0.5% 200 75%
250 1% 250 94% 0.5% 250 75%
300 1% 253 95% 0.5% 300 94%
500 1% 300 95% 0.5% 500 94%
750 1% 312 95% 0.5% 527 95%
1000 1% 345 95% 0.5% 601 95%
*

The minimum number of animals with clinical signs in a herd is one. Therefore, the values provided here for the design prevalence is the result of the ratio between 1 and the herd size.