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. 2021 Oct 28;93(2):188–195. doi: 10.1136/jnnp-2021-327412

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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OCT results stratified by ON status (tested with Spectralis devices): boxplots of mean OCT values with individual eyes (jitter) in HC (left, green), AQP4-IgG cohort (middle) and MOG-IgG cohort (right). Seropositive patients with a history of ON are highlighted with light yellow and seropositive patients without a history of ON are highlighted in orange. (A) pRNFL; (B) GCIP; (C) INL; (D) OPL; (E) ONL; and (F) PR. AQP4, aquaporin-4; GCIP, ganglion cell and inner plexiform layer; INL, inner nuclear layer; MOG, myelin-oligodendrocyte-glycoprotein; OCT, optical coherence tomography; ONL, outer nuclear layer; OPL, outer plexiform layer; PR, photoreceptive layer; pRNFL, peripapillary retinal nerve fibre layer.