. 2021 Oct 28;93(2):188–195. doi: 10.1136/jnnp-2021-327412

Table 3.

OCT results in patients who were AQP4-IgG seropositive stratified by history of on (Spectralis devices only)

	AQP4-ON	AQP4-NON	MOG-ON	MOG-NON	AQP4-ON vs AQP4-NON			AQP4-ON vs HC			AQP-NON vs HC			AQP4-ON vs MOG-ON			AQP4-NON vs MOG-NON
	AQP4-ON	AQP4-NON	MOG-ON	MOG-NON	B	SE	P	B	SE	P	B	SE	P	B	SE	P	B	SE	P
Number of eyes	232	85	43	12	B	SE	P	B	SE	P	B	SE	P	B	SE	P	B	SE	P
pRNFL in µm (mean±SD)	72.84±24.47	96.09±12.99	68.03±22.95	95.33±7.32	−25.18	3.93	<0.001	−29.56	3.57	<0.001	−9.29	5.15	0.07	2.63	6.12	0.667	6.03	5.44	0.275
GCIP in µm (mean±SD)	62.94±12.73	77.11±7.56	63.45±11.96	75.88±6.01	−14.74	2.06	<0.001	−19.60	1.49	<0.001	−0.50	1.48	0.735	−4.00	3.20	0.215	3.22	3.36	0.344
OPL in µm (mean±SD)	25.06±2.01	24.71±1.79	25.28±2.08	24.45±1.55	0.26	0.38	0.498	0.34	0.26	0.184	0.09	0.38	0.804	0.34	0.51	0.509	−0.12	0.96	0.899
ONL in µm (mean±SD)	62.53±7.45	63.14±6.62	66.09±8.08	59.76±4.58	−0.19	1.49	0.901	−0.18	0.92	0.847	−0.82	1.40	0.560	−2.84	2.12	0.183	2.76	3.58	0.446
OPNL in µm (mean±SD)	87.58±7.67	87.85±6.78	84.21±5.68	91.37±8.69	0.00	1.53	0.879	0.27	0.95	0.775	0.37	1.42	0.794	−2.51	2.21	0.259	2.67	3.51	0.450
PR in µm (mean±SD)	80.89±2.93	79.80±2.94	82.01±3.45	79.62±3.58	0.75	0.57	0.187	−0.19	0.36	0.595	−1.08	0.59	0.071	−0.58	0.77	0.454	1.36	1.44	0.348

AQP4, aquaporin-4; B, estimate; GCIP, ganglion cell and inner plexiform layer; HC, healthy control; MOG, myelin-oligodendrocyte-glycoprotein; NON, non-optic neuritis; ON, optic neuritis; ONL, outer nuclear layer; OPL, outer plexiform layer; OPNL, outer plexiform and nuclear layer; PR, photoreceptor layer; pRNFL, peripapillary retinal nerve fibre layer.