Skip to main content
. 2021 Sep 28;93(2):169–179. doi: 10.1136/jnnp-2021-326630

Figure 3.

Figure 3

Thalamic tract-of-interest changes in FC in PD-VH compared with those without hallucinations at baseline and during longitudinal follow-up. (A) Baseline visit. Reduction (mean, 95% CI) in FC visualised for patients with PD-VH compared with patients with PD without hallucinations (PD non-VH). Tracts with significantly reduced FC (FDR-corrected p value<0.05) are shown in dark red (right MDm and right CeM), while tracts where there are no significant changes in FDC are plotted in grey. (B) Visit 2 (18 months follow-up). Reduction (mean, 95% CI) in FC visualised for PD-VH compared with PD non-VH. Tracts with significantly reduced FC (FDR-corrected p value<0.05) are shown in colour, while tracts with no significant changes in FDC are plotted in grey. White matter tracts from all but three thalamic subnuclei (Pc, Pt and VM bilaterally) showed more severe volume loss in PD-VH compared with PD non-VH at longitudinal follow-up. Bilaterally tracts originating in the VM nuclei showed significantly less volume loss in PD-VH compared with PD non-VH. AV, anteroventral; CeM, central medial; CL, central lateral; CM, centromedian; L_Sg, limitans; LD, laterodorsal; LGN, lateral geniculate; LP, lateral posterior; MDl, mediodorsal medial parvocellular, MDm, mediodorsal medial magnocellular; MGN, medial geniculate; MVRe, reuniens medial ventral; Pc, paracentral; PD, Parkinson’s disease; Pf, parafascicular; PuA, pulvinar anterior; PuI, pulvinar inferior; PuL, pulvinar lateral; PuM, pulvinar medial; VA, ventral anterior; VAmc, ventral anterior Pt, paratenial; magnocellular; VH, visual hallucination; VLa, ventral lateral anterior; VLp, ventral lateral posterior; VPL, ventral posterolateral; VM, ventromedial.