Table 3.

Mitotic index in bone marrow cells of male BALB/c mice treated with Fe₂O₃, Al₂O₃, and Cu nanoparticles

Group	Dose (mg/kg)	No. of analysed metaphases	No. of mitotic cells	Mitotic index (%)
Fe2O3 nanoparticles
NC	0	5000	409	8.180±0.540
PC	2	5000	61	1.220±0.259*
1	75	5000	399	7.980±0.370
2	150	5000	395	7.900±0.709
3	300	5000	401	8.080±1.180
Al2O3 nanoparticles
NC	0	5000	417	8.340±0.351
PC	2	5000	58	1.160±0.288*
1	75	5000	403	8.060±0.517
2	150	5000	409	8.180±0.687
3	300	5000	399	7.980±0.991
Cu nanoparticles
NC	0	5000	411	8.220±0.277
PC	2	5000	54	1.080±0.238*
1	5	5000	406	8.120±0.868
2	10	5000	399	7.980±0.673
3	15	5000	309	6.180±0.802*

^*Data are expressed as means ± SD (n=5).

^*significant difference from negative control (P<0.05); Mitotic index (%) – number of mitotic cells per total number of cells observed × 100; NC – negative control; PC – positive control (single ip dose of 2 mg/kg mitomycin C)