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. 2022 Jan 4;9:738916. doi: 10.3389/fcell.2021.738916

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Copyright © 2022 Cevatemre, Ulukaya, Dere, Dilege and Acilan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PDHi-induced morphological changes in A549 cancer cells. (A) Cells treated with PDHi for 48–72 h (Supplementary Figure S6 for morphological changes in HT29 and MCF7 cancer cells) at indicated doses and were photographed under phase contrast microscope (magnification 100×). (B). Phalloidin staining indicated F-actin (red) reorganization in PDHi treated A549 cells. DAPI was used to stain DNA (blue, magnification 400×).