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. Author manuscript; available in PMC: 2022 Jan 24.
Published in final edited form as: Exp Neurol. 2020 Sep 17;334:113465. doi: 10.1016/j.expneurol.2020.113465

Figure 3. A representative example of the sustained impact of intravenous delivery of ampakine CX717 on phrenic nerve activity, arterial blood pressure and heart rate at 8 weeks following C2Hx injury.

Figure 3.

Approximately 15-seconds of data are shown at baseline (BL), and 2-, 15-, 30-, and 60-minutes following CX717 administration. Note the sustained and bilateral increase in inspiratory phrenic burst amplitude. Panels a (baseline) and b (60-minutes post-CX717) provide expanded time scale traces taken from the areas indicated by the gray box. ETCO2 = end-tidal CO2, HR = heart rate; ABP = arterial blood pressure (ABP), RR = respiratory rate; ʃPhr = integrated phrenic signal; CL = contralateral to C2Hx; IL = ipsilateral to C2Hx. The phrenic nerve burst amplitude can be considered as arbitrary units (au).