Table 1.
CX717 | CX717 + Hypoxia | HPCD + Hypoxia | |
---|---|---|---|
| |||
Age at experiment (weeks) | |||
2 wk post-Hx | 13.9±1.6 | 13.4±1.4 | 14.0±1.5 |
8 wk post-Hx | 18.6±1.5 | 18.6±1.8 | 18.2±1.7 |
Age at time of surgery (weeks) | |||
2 wk post-Hx | 11.8±1.7 | 11.1±1.3 | 11.8±1.5 |
8 wk post-Hx | 10.4±1.4 | 10.6±1.6 | 10.2±1.6 |
Weeks post injury | |||
2 wk post-Hx | 2.1±0.2 | 2.3±0.4 | 2.3±0.3 |
8 wk post-Hx | 8.2±0.6 | 7.9±0.6 | 8.0±0.5 |
| |||
Weight at experiment (grams) | |||
2 wk post-Hx | 331 ± 32 | 317 ± 34 | 318 ± 28 |
8 wk post-Hx | 393±28 | 409±22 | 392±35 |
Weight at Hx (grams) | |||
2 wk post-Hx | 301±38 | 301±33 | 307±15 |
8 wk post-Hx | 329±37 | 320±20 | 391±33 |
| |||
ʃBurst Amplitude (mV) | |||
Ipsilateral, 2 wk post-Hx | 1.6±1.1 | 1.9±0.1.2+ | 2.5±1.4+ |
Contralateral, 2 wk post-Hx | 9.1±3.3 | 9.1±6.7 | 7.8±2.2 |
Ipsilateral, 8 wk post-Hx | 1.4±0.6 | 2.8±2.1 | 2.0±1.7 |
Contralateral, 8 wk post-Hx | 7.8±2.6 | 8.7±5.3 | 12.0±4.4 |
| |||
Frequency (per minute) | |||
2 wk post-Hx | 52±5 | 52±6 | 50±5 |
8 wk post-Hx | 51±6 | 53±6 | 54±3 |
| |||
Heart Rate (per minute) | |||
2 wk post-Hx | 438±11 | 436±23 | 451±17 |
8 wk post-Hx | 417±21* | 423±14 | 411±14* |
| |||
Mean Arterial Pressure (mmHg) | |||
2 wk post-Hx | 114±9 | 126±20 | 114±15 |
8 wk post-Hx | 141±20* | 145±23 | 141±25* |
Data are presented as Mean ± SD.
different than the corresponding 2-week time point within the treatment group, p<0.05;
does not include experiments were the baseline phrenic burst amplitude was zero