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. Author manuscript; available in PMC: 2022 Jan 24.
Published in final edited form as: Neurosci Lett. 2020 Dec 31;744:135562. doi: 10.1016/j.neulet.2020.135562

Fig. 1.

Fig. 1.

Overview of Mrgprs Signaling Pathways. Mrgprs have been found to utilize Gαq/11, Gαi/o, Gαs, and Gβγ pathways. Activation of G proteins stimulates the intracellular signaling pathways and leads to the opening of transduction channels.