eTable 2:

Sensitivity, Specificity, Positive Predictive Value, Negative Predictive Value, observed and predicted 30-day mortality for revised Risk Analysis Index (RAI) in American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) datasets (2005–2014)

RAI-rev Threshold	N	Frailty Prevalence (%)	Sensitivity (%)	Specificity (%)	Positive Predictive Value (%)	Negative Predictive Value (%)	Observed 30-day mortality (%)	Predicted 30-Day Mortality (%)
0	9,484	100	100	0	1	-	0.0	0
1	16,485	99.3	100	0.7	1	100	0.0	0
2	165	98.1	100	1.9	1	100	1.2	0
3	7,091	98.1	100	1.9	1	100	0.0	0
4	40,009	97.6	100	2.4	1	100	0.0	0
5	325	94.7	99.9	5.3	1	100	0.6	0
6	39,645	94.7	99.9	5.4	1	100	0.0	0.1
7	15,765	93.6	99.8	8.2	1	100	0.1	0.1
8	52,414	89.8	99.6	9.4	1.1	100	0.0	0.1
9	19,664	88.4	99.5	13.2	1.1	100	0.1	0.1
10	66,272	83.6	99.4	14.6	1.1	100	0.1	0.1
11	25,423	81.8	99.1	19.4	1.2	100	0.1	0.1
12	79,957	76	98.9	21.3	1.2	99.9	0.1	0.1
13	33,856	73.6	98.4	27	1.3	99.9	0.1	0.2
14	83,965	67.6	98.1	29.5	1.3	99.9	0.1	0.2
15	44,256	64.4	97.4	35.6	1.4	99.9	0.2	0.2
16	79,427	58.7	96.8	38.8	1.5	99.9	0.2	0.3
17	54,733	54.8	95.6	44.5	1.6	99.9	0.3	0.3
18	76,211	49.3	94.5	48.5	1.8	99.9	0.3	0.3
19	61,156	44.9	92.9	54	1.9	99.9	0.4	0.4
20	67,425	40	91.3	58.4	2.1	99.9	0.4	0.5
21	64,117	35.4	89.3	63.3	2.3	99.8	0.5	0.6
22	54,202	31.5	86.8	67.9	2.6	99.8	0.7	0.7
23	62,694	27	84.2	71.8	2.8	99.8	0.7	0.8
24	44,889	23.8	80.9	76.4	3.2	99.8	0.9	0.9
25	52,819	20	77.8	79.6	3.6	99.7	1.0	1.1
26	32,829	17.7	73.9	83.4	4.1	99.7	1.4	1.2
27	43,339	14.5	70.5	85.7	4.6	99.7	1.4	1.4
28	19,676	13.1	66	88.8	5.4	99.6	2.2	1.7
29	31,811	10.8	62.7	90.2	5.9	99.6	2.0	2
30	11,466	10	58	92.5	7	99.6	3.6	2.3
31	19,236	8.6	54.9	93.3	7.4	99.5	3.0	2.7
32	9,994	7.9	50.6	94.6	8.4	99.5	3.9	3.1
33	11,072	7.1	47.7	95.3	9.1	99.5	4.2	3.6
34	9,901	6.4	44.2	96.1	10	99.4	4.5	4.2
35	9,195	5.8	40.9	96.8	11	99.4	5.4	4.9
36	6,879	5.3	37.1	97.4	12.3	99.4	6.6	5.7
37	7,137	4.7	33.7	97.9	13.5	99.3	6.4	6.6
38	5,154	4.4	30.3	98.4	15.4	99.3	8.8	7.7
39	3,169	4.2	27	98.7	17	99.3	11.5	8.9
40	2,857	3.9	24.2	98.9	17.9	99.3	12.9	10.2
41	2,430	3.8	21.5	99.1	18.9	99.2	14.2	11.8
42	2,443	3.6	18.9	99.3	19.8	99.2	14.1	13.6
43	2,113	3.4	16.3	99.4	21.1	99.2	15.2	15.5
44	1,709	3.3	14	99.5	22.6	99.2	14.9	17.7
45	1,598	3.2	12.1	99.6	24.6	99.1	17.8	20.1
46	1,145	3.1	9.9	99.7	26.8	99.1	20.1	22.8
47	768	3.1	8.2	99.8	28.9	99.1	21.6	25.7
48	585	3	7	99.8	30.7	99.1	23.6	28.9
49	537	3	6	99.9	32.3	99.1	24.8	32.2
50	480	3	5	99.9	34.5	99.1	29.4	35.8
51	330	2.9	3.9	99.9	36.1	99.1	29.4	39.5
52	271	2.9	3.2	99.9	38.1	99.1	30.3	43.4
53	231	2.9	2.6	100	40.6	99.1	36.4	47.3
54	176	2.9	2	100	42.2	99.1	35.2	51.2
55	109	2.9	1.5	100	44.9	99.1	43.1	55.2
56	85	2.9	1.1	100	45.5	99	47.1	59.1
57	51	2.9	0.8	100	45	99	27.5	62.8
58	43	2.9	0.7	100	49.5	99	41.9	66.5
59	53	2.9	0.6	100	51.6	99	50.9	69.9
60	33	2.9	0.4	100	51.9	99	48.5	73.1
61	23	2.9	0.3	100	53.5	99	52.2	76.1
62	13	2.9	0.2	100	54.2	99	53.9	78.9
63	12	2.9	0.1	100	54.3	99	58.3	81.4
64	9	2.8	0.1	100	52.2	99	55.6	83.7
65	3	2.8	0.1	100	50	99	33.3	85.7
66	1	2.8	0	100	54.5	99	0.0	87.6
67	5	2.8	0	100	60	99	80.0	89.2
68	3	2.8	0	100	40	99	66.7	90.6
69	1	2.8	0	100	0	99	0.0	91.9
70	1	2.8	0	100	0	99	0.0	93