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. 2022 Jan 24;53:6. doi: 10.1186/s13567-022-01024-1

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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LPS induced hepatotoxicity in chickens. A Changes in AST activity (a), ALT activity (b), and DBILI content (c) in serum after LPS treatment (60 mg/kg). ** P < 0.01 vs. the control group. B Histopathological analysis of chicken liver. Histopathological examination results of liver samples from two experimental groups are shown (scale bar = 50 μm), and the images are displayed at 100 × and 400 × the original magnification. The experimental groups were the control group (a) and LPS-treated group (b). C Ultrastructural analysis of chicken liver. Transmission electron microscopic examination of liver samples from two experimental groups (scale bar = 2 μm). a shows the control group, and b shows the LPS-treated group. ALT: alanine aminotransferase; AST: aspartate aminotransferase; DBILI: direct bilirubin.