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. 2022 Jan 24;17:15. doi: 10.1186/s13014-022-01984-w

Table 2.

Molecular features of analyzed patients

Molecular features Specification All LTS (n = 91) STS-1 (n = 91) LTS (subgroup, n = 80) STS-2 (n = 80)
GFAP* (%) Positive 73.8 94.4 61.6 93.5 64.6
Partially negative 25.2 5.6 37.0 6.5 33.8
Negative 1.0 0 1.4 0 1.5
MGMT* (%) Methylated 53.7 70.9 49.0 71.1 37.2
Unmethylated 46.3 29.1 51.0 28.9 62.8
IDH1R132H* (%) Positive 11.0 15.4 7.3 16.7 11.9
Negative 89.0 84.6 92.7 83.3 88.1
MIB1

Median

(range)

20

(3–90)

18

(5–60)

25

(8–50)

18

(5–60)

25

(3–90)

Ki67

Median

(range)

25

(8–90)

20

(8–60)

30

(10–90)

25

(10–60)

25

(10–80)

Ki67/MIB1

Median

(range)

25

(3–90)

18

(5–60)

30

(8–90)

20

(5–60)

25

(3–90)

GFAP/MGMT* (%) GFAP+/MGMT+ 42 66.0 28.6 65.9 25.0
GFAP+/MGMT− 34 30.2 35.7 29.5 37.5
GFAP−/MGMT+ 10 3.8 16.7 4.5 12.5
GFAP−/MGMT− 13 0 19.0 0 25.0

*Results refer to patients in whom tissue was available