Table 2.
Demographics
| Study, Year | Age PCC3 | Age PCC4 | Male PCC3 (%) | Male PCC4 (%) | Weight PCC3 (kg) | Weight PCC4 (kg) |
|---|---|---|---|---|---|---|
| Al-Majzoub et al., 2016 [20] | 79 [70–87] | 82 [76–88] | 19 (54.3%) | 10 (55.5%) | 81.3 (15.0) | 74.5 (12.7) |
| DeAngelo et al., 2018 [22] | 68.9 (14.2) | 70.0 (13.7) | 38 (66.7%) | 14 (40.6%) | 89.3 (24.9) | 80.8 (29.1) |
| Fischer et al., 2018 [24] | 77 [73–82] | 80 [73–86] | 17 (42.5%) | 34 (54%) | NR | NR |
| Holt et al., 2018 [25] | 74 (10.8) | 57 (14.7) | 43 (55.8%) | 29 (50.9%) | 87.9 (26.9) | 84.9 (22.6) |
| Jones et al., 2016 [27] | 75.5 [64.0–83.0] | 72.5 [58.5–80.0] | 45 (53.6%) | 38 (59.4%) | 84.8 [70.2–100.8] | 82.5 [72.4–100.3] |
| Kuroski et al., 2017 [28] | 74.5 (NR) | 76.2 (NR) | 36 (53.0%) | 37 (53.6%) | 78.7 (NR) | 85.7 (NR) |
| Mangram et al., 2016 [30] | 76 (13) | 77 (8) | 25 (54.3%) | 10 (55.5%) | 80 (22) | 83 (18) |
| Margraf et al., 2020 [31] | 74.0 [62.0–80.0] | 66.0 [57.0–82.0] | 36 (63.2%) | 12 (52.2%) | 81.4 [72.1–94.4] | 77.8 [64.7–97.8] |
| Mohan et al., 2018 [32] | 73.54 (28–102, 76.50) Mean (range, median) (both groups) | 73.54 (28–102, 76.50) Mean (range, median) (both groups) | 83 (65%) (both groups) | 83 (65%) (both groups) | 77.9 (NR) (both groups) | 77.9 (NR) (both groups) |
| Voils et al., 2015 [33] | 71.8 (13.1) | 70.4 (13.4) | 31 (55%) | 64 (55%) | 85 (25) | 88 (23) |
| Cang et al., 2014 [21] | NR | NR | NR | NR | NR | NR |
| Di Napoli et al., 2014 [23] | NR | NR | NR | NR | NR | NR |
| Kotsianas et al., 2015 [26] | NR | NR | NR | NR | NR | NR |
| Peck et al., 2016 [29] | NR | NR | NR | NR | NR | NR |
| Wagner et al., 2019 [34] | 68 [59, 80] (both groups) | 68 [59, 80] (both groups) | NR | NR | NR | NR |
Age and weight reported as mean (SD), median [IQR], or mean (min-max, median)
PCC prothrombin complex concentrate, PCC3 3 factor PCC, PCC4 4 factor PCC