Table 4.

The average changes in ΔPNIF and ΔPEF (L min⁻¹) during each exposure scenario and compared to the FA exposure

	PNIF			PEF
	Estimated mean (95%CI)	Beta (95% CI)	p value	Estimated mean (95%CI)	Beta (95% CI)	p value
FA	10.3 [4.1, 16.6]	Ref	ref	2.2 [− 5.1, 9.5]	Ref	ref
HVONOx	− 7.7 [− 14.4, − 1.1]	− 18.1 [− 27.3, − 8.8]	< 0.001	− 2.5 [− 10.2, 5.3]	− 4.6 [− 15.6, 6.3]	0.40
HVOPM+NOx	2.9 [− 3.4, 9.1]	− 7.4 [− 15.6, 0.8]	0.08	4.7 [− 2.4, 11.9]	2.5 [− 7.1, 12.2]	0.60

Estimated average changes in ΔPNIF and ΔPEF (L min⁻¹) during each exposure scenario (estimated mean) and differences between the two HVO exposures and FA exposure (beta). The beta values (L min⁻¹) and significance (p value) are based on the linear mixed model with exposure order correction. Values within brackets are the 95% CI