TABLE 1.
Demographic characteristics and clinical data between KOA patients and HCs
| Characteristic | End‐stage KOA | Healthy controls | p‐value |
|---|---|---|---|
| VBM (n) | 37 | 37 | / |
| Male/female | 3/34 | 7/30 | .177 a |
| Age (mean ± SD, years) | 71.6 ± 5.6 | 69.5 ± 5.1 | .098 |
| MoCA scores | 28.3 ± 1.3 | 28 ± 1.3 | .527 |
| WOMAC | 130.0 ± 9.2 | — | — |
| FC (n) | 23 | 29 | / |
| Male/female | 3/20 | 7/22 | .318 a |
| Age (mean ± SD, years) | 73.2 ± 5.5 | 69.4 ± 5.3 | .958 |
| Total intracranial volume (mean ± SD, mL) | 1305.7 ± 120.6 | 1280.8 ± 88.6 | .314 |
Abbreviations: FC, functional connectivity; HCs, healthy controls; KOA, knee osteoarthritis; MoCA, Montreal Cognitive Assessment; VBM, voxel‐based morphometry; WOMAC, The Western Ontario and McMaster Universities Osteoarthritis Index.
a
Mann–Whitney U test.