TABLE 2.
HHV-6 and HHV-7 dual primary infection in British children: antibody responses and detection of DNA from both viruses
| Patient no. | Age (mo) | Day after onset of symptoms | Serum or plasma
|
|||||
|---|---|---|---|---|---|---|---|---|
| HHV-6 IgG titera
|
HHV-6 DNA | HHV-7 IgG titera
|
HHV-7 DNA | |||||
| Without urea | With urea | Without urea | With urea | |||||
| 13 | 10 | 1c | 16 | NTb | − | <8 | NT | − |
| 14d | 2,048 | 32 | NT | 128 | <16 | NT | ||
| 14 | 12 | 3c | NT | NT | + | <8 | <8 | − |
| 4e | <16 | <16 | NT | NT | NT | NT | ||
| 19 | 2,048 | 64 | NT | 256 | <16 | NT | ||
a
Those sera whose antibody titers were reduced eightfold or greater by urea are defined as having low-avidity antibody and the results are highlighted in bold. Those sera whose titers were reduced fourfold or less by urea are defined as having high-avidity antibody.
b
NT, not tested.
c
Cerebrospinal fluid contained HHV-6 DNA but not HHV-7 DNA.
d
Saliva contained HHV-7 DNA but not HHV-6 DNA.
e
Saliva contained HHV-6 DNA and HHV-7 DNA.