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. 2022 Jan 26;28(1):2–13. doi: 10.1097/PPO.0000000000000567

TABLE 3.

Venetoclax Dosing With Azole Antifungals

Standard Dose Moderate CYP3A4 or P-Gp Inhibitor, e.g., Isavuconazole Strong CYP3A4 Inhibitor,
e.g., Voriconazole, Posaconazole
Echinocandin
100 mg 50 mg 10 mg No dose reduction needed
200 mg 100 mg 20 mg
400 mg ≤200 mg 50–70 mg
(50 mg with posaconazole)
600 mg* ≤300 mg 50–70 mg

*For venetoclax with LDAC or 5 + 2 regimen of cytarabine with Ida.