TABLE 3.
Standard Dose | Moderate CYP3A4 or P-Gp Inhibitor, e.g., Isavuconazole | Strong CYP3A4 Inhibitor, e.g., Voriconazole, Posaconazole |
Echinocandin |
---|---|---|---|
100 mg | 50 mg | 10 mg | No dose reduction needed |
200 mg | 100 mg | 20 mg | |
400 mg | ≤200 mg | 50–70 mg (50 mg with posaconazole) |
|
600 mg* | ≤300 mg | 50–70 mg |
*For venetoclax with LDAC or 5 + 2 regimen of cytarabine with Ida.