Figure 3.

Torcetrapib increases the apoA1 concentrations of subspecies of HDL (high-density lipoprotein) that lacks both apoE and apoC3, the subspecies of HDL that contains both apoE and apoC3, and the subspecies of HDL that contains apoC3 but not apoE. Torcetrapib had no effect on the subspecies of HDL that contains apoE but not apoC3. Atorvastatin was given as a background medication to all groups to control and equalize LDL (low-density lipoprotein)-cholesterol. N=14. P values above plots are for change from baseline. P value below bracket compares HDL that contains both apoE and apoC3 to HDL that contains apoE and lacks apoC3.