Figure 2.

Effect of methimazole alone on the intestinal microbiota of patients with GD. (A) The effects of mebendazole alone on intestinal microbiota α diversity, including shannon and Simpson index, the same color points represent the volunteers at different time points. (B) Principal coordinates analysis (PCoA) based on Bray-Curtis distances for metagenomic species, with points of the same color representing the volunteer at different time points. (C) MAGs with significant differences from baseline at 6 months of treatment. (D) Gut microbial metabolic pathways that produced significant differences from methimazole treatment at 6 months of treatment at baseline. (E) Strains with significant differences from baseline at 6 months of treatment.