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. 2021 Sep 2;2(11):1844–1851. doi: 10.34067/KID.0003682021

Table 1.

Examples of markers commonly used to identify populations of myeloid cell types in mice and humans

Markers Mouse Human
Monocyte CD11b, Ly6C, CD192 (CCR2), CX3CR1 CD11b, CD14, CD16
Macrophage CD11b, F4/80, CD68, CD64 CD11b, CD68, CD163
 Proinflammatory CD86, MHCII CD86, HLA-DR
 Anti-inflammatory CD206 (MRC1), IL-4R CD206 (MRC1), IL-4R
 Tissue resident CD192 (CCR2), CD206 (MRC1), CD68, CD74, CD81 CD192 (CCR2), CD68, CD74, CD81
Dendritic cell CD11c, CD11b, MHCII CD11c, CD11b, HLA-DR
 Conventional CX3CR1, CD103 CD1c (BDCA1), HLA-DR
 Plasmacytoid Ly-49Q, CD317 (Bst2) CD123 (IL-3Rα), CD303 (BDCA2)
Neutrophil CD11b, Ly6G, CD18 CD11b, CD16, CD32, CD66b
Eosinophil CD170 (Siglec-F), CD193 (CCR3) CD329 (Siglec-8), CD193 (CCR3)
Basophil CD123 (IL-3Rα), FcεRIα CD123 (IL-3Rα), FcεRIα
Mast cell CD117 (c-Kit), FcεRIα CD32, CD117 (c-Kit), FcεRIα

Detection of myeloid (CD45+) cell types by flow cytometry. Combinations and level of marker expression can vary with subtype/state of activation. Ly6C, lymphocyte antigen 6; CCR2, C-C chemokine receptor type 2; CX3CR1, CX3 chemokine receptor 1; MHCII, major histocompatibility complex II; HLA-DR, human leukocyte antigen–DR isotype; MRC1, mannose receptor C-type 1; IL4R, interleukin-4 receptor; BDCA1, blood dendritic cell antigen 1; Bst2, bone marrow stromal cell antigen 2; IL-3Rα, interleukin-3 alpha receptor; BDCA2, blood dendritic cell antigen 2; Ly6G, lymphocyte antigen 6 complex locus G6D; CCR3, C-C chemokine receptor type 3; FcεRIα, Fc epsilon alpha receptor I.