Table 4.
Unadjusted odds ratios for the likelihood of arteriovenous fistula nonmaturation on the basis of demographic, clinical, vascular, and immune factors
| Variable | Unadjusted Odds Ratio | 95% Confidence Interval | P Value |
|---|---|---|---|
| Age, per 10 yr increase | 0.94 | 0.71 to 1.25 | 0.68 |
| Sex, female | 3.20 | 1.47 to 6.95 | 0.005 |
| Black race | 4.49 | 1.61 to 12.54 | 0.002 |
| HTN, yes versus no | 0.52 | 0.06 to 4.84 | 0.55 |
| DM, yes versus no | 0.59 | 0.28 to 1.24 | 0.16 |
| CAD, yes versus no | 1.36 | 0.45 to 4.07 | 0.57 |
| CVD, yes versus no | 0.59 | 0.19 to 1.81 | 0.36 |
| PVD, yes versus no | 1.44 | 0.37 to 5.64 | 0.59 |
| LVEF <55%, yes versus no | 0.95 | 0.33 to 2.67 | 0.92 |
| BMI in kg/m2, per 5 point increase, yes versus no | 0.96 | 0.74 to 1.24 | 0.78 |
| History of solid organ transplant, yes versus no | 1.39 | 0.51 to 3.63 | 0.51 |
| History of blood transfusion, yes versus no (females only) | 0.90 | 0.42 to 1.92 | |
| History of 2 versus 0 pregnancies | 4.88 | 1.06 to 22.38 | 0.03 |
| Taking immunosuppressant medications, yes versus noa | 0.80 | 0.30 to 1.93 | 0.62 |
| Current or former tobacco user, yes versus no | 0.66 | 0.30 to 1.45 | 0.30 |
| Taking anticoagulation, yes versus nob | 0.94 | 0.44 to 1.96 | 0.8 |
| Upper arm AVF location | 0.91 | 0.42 to 1.96 | 0.80 |
| Arterial diameter, per 1 mm increase | 0.78 | 0.54 to 1.09 | 0.15 |
| Venous diameter, per 1 mm increase | 0.61 | 0.37 to 0.95 | 0.03 |
| Class I PRA, per 10% increase | 1.14 | 0.96 to 1.34 | 0.12 |
| Class II PRA, per 10% increase | 1.27 | 1.06 to 1.58 | 0.01 |
HTN, hypertension; DM, diabetes mellitus; CAD, coronary artery disease; CVD, cerebrovascular disease; PVD, peripheral vascular disease; LVEF, left ventricular ejection fraction; BMI, body mass index; PRA, panel reactive antibodies.
Immunosuppressant medications included steroids, calcineurin inhibitors, and mycophenolate mofetil.
Anticoagulation included aspirin, warfarin, clopidogrel, and rivaroxaban.