Table 1.
Percentage of inhibition (%) | Cell viability
|
Total ROS Level
|
||
---|---|---|---|---|
A549 | rBCECs | A549 | rBCECs | |
Gd@C82(OH)22 | 59.1±3.3 | 54.1±1.9 | 94.6±2.6 | 93. 5±3.4 |
C60(OH)22 | 37.1±3.5 | 35.5±3.3 | 74.1±3.5 | 72.7±2.9 |
C60(C(COOH)2)2 | 17.2±3.8 | 27.8±1.9 | 47.2±2.2 | 20.4±1.8 |
Note: For measuring effects on cell viability, the cells were treated with 100 μmol/ml fullerene derivatives before incubation with 50 μM H2O2. Cell viability was assessed by measurement of mitochondrial dehydrogenase activity. For measurement of intracellular ROS, the same conditions for incubation with H2O2 were used. Levels of intracellular ROS were determined by flow cytometry.