Figure 4. Lateral view of the cortex, depicting the color-coded vertex-wise z-values for the top genetic loci identified in the discovery vertex-wise MOSTest analysis.
(A): top lead variant (rs34680120, chr15:39664000, effect direction of C allele is shown, frequency of C allele = 0.94) associated with cortical surface area in discovery (top) and replication (bottom) samples. (B): top lead variant (rs8033007, chr15:39619661, effect direction of G allele is shown, frequency of G allele = 0.91) associated with cortical thickness in discovery (top) and replication (bottom) samples.