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Pharmacological agents for manipulation of actin polymerization.
| Natural toxin | Action | Net effect |
|---|---|---|
| Latrunculin | Binds G-actin monomers to prevent polymerization | Depolymerization |
| Cytochalasin | Binds to barbed (+) end of F-actin to prevent polymerization | Depolymerization |
| Phalloidin | Stabilizes F-actin by inhibiting depolymerization | Stabilization/polymerization |
| Jasplakinolide | Stabilizes F-actin and induces polymerization | Polymerization |
