TABLE 3.
Upregulated proteins in CLTI amputation specimens identified at both sites
| University of Florida | East Carolina University | ||||
|---|---|---|---|---|---|
| Gene ID | Gene description | Fold change (CLTI/Control) | P‐value | Fold change (CLTI/Control) | P‐value |
| ADH1B | All‐trans‐retinol dehydrogenase [NAD(+)] ADH1B | 2.2 | 0.00023 | 3.9 | 0.00002 |
| AKR1C1 | Aldo‐keto reductase family 1 member C1 | 1.8 | 0.00620 | 5.4 | 0.02791 |
| AMBP | Protein AMBP | 2.2 | 0.00974 | 4.5 | <0.00001 |
| CFL1 | Cofilin‐1 | 1.3 | 0.00388 | 7.7 | <0.00001 |
| DDX39B | Isoform 2 of Spliceosome RNA helicase DDX39B | 1.4 | 0.01493 | 5.7 | <0.00001 |
| F13A1 | Coagulation factor XIII A chain | 2.6 | 0.00048 | 18.7 | <0.00001 |
| FTL | Ferritin light chain | 3.4 | 0.00001 | 18.4 | <0.00001 |
| MYH10 | Isoform 4 of Myosin‐10 | 1.5 | 0.01277 | 32.6 | <0.00001 |
| MYO1C | Unconventional myosin‐Ic | 1.5 | 0.00650 | 24.3 | <0.00001 |
| PA2G4 | Proliferation‐associated protein 2G4 | 1.4 | 0.00163 | 4.8 | <0.00001 |
| PPIA | Peptidyl‐prolyl cis‐trans isomerase | 1.9 | 0.00002 | 7.6 | <0.00001 |
| TNPO1 | Transportin‐1 | 1.4 | 0.02530 | 3.3 | <0.00001 |