. 2021 Mar 30;204(11):1274–1285. doi: 10.1164/rccm.202105-1302OC

Table 5.

Comparison of 90-Day Mortality in Subgroups Stratified by Corticosteroid in ARDS Subphenotypes and COVID-19–related ARDS Classes

Corticosteroid Use	ARDS Subphenotype		P Value
Corticosteroid Use	Hypoinflammatory	Hyperinflammatory	P Value
Yes	115/226 (51%)	57/94 (61%)	0.0295
No	51/113 (45%)	37/48 (77%)	0.0295
Corticosteroid Use	COVID-19–related ARDS Class		P Value
Corticosteroid Use	Class 1	Class 2	P Value
Yes	120/244 (49%)	52/76 (68%)	0.0273
No	58/127 (46%)	30/34 (88%)	0.0273

Definition of abbreviations: ARDS = acute respiratory distress syndrome; COVID-19 = coronavirus disease.

P value represents the interaction between ARDS subphenotype or COVID-19–related ARDS class and corticosteroid exposure in a logistic regression model with 90-day mortality as the dependent variable.