Kaplan-Meier survival curves of time to next PEx requiring intravenous antimicrobials ascertained from the U.S. Cystic Fibrosis Foundation patient registry: (A) Early robust responders per protocol (10 d, n = 104; 14 d, n = 105). (B) Non–early robust responders, intent to treat (14 d, n = 346; 21 d, n = 343). ERR = early robust responder; ITT = intent to treat; PEx = pulmonary exacerbations; PP = per protocol; NERR = non–early robust responder.