Table 5.
Management Approach |
Mild patients not requiring hospital admission |
1. Continuation of current immunosuppression with calcineurin inhibitor and prednisone |
2. Decrease in antimetabolite dose (25%–100%) |
3. Monoclonal neutralizing antibody treatment (LY-CoV555 or REGN-COV2) |
Moderate patients requiring hospital admission |
1. Continuation of current immunosuppression with calcineurin inhibitor treatment with 25%–50% dose reduction |
2. Dexamethasone 6 mg daily for 5–10 days |
3. Hold antimetabolite |
Severe patients requiring intensive care unit admission |
1. Holding calcineurin inhibitor and antimetabolite |
2. Dexamethasone 6 mg daily for 5–10 days |
REGN-COV2, casirivimab and imdevimab.