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. 2022 Jan 24;37(5):1218–1225. doi: 10.1007/s11606-021-07379-z

Table 2.

Most Bothersome Persistent Symptoms, Stratified by Pre-COVID Comorbid Conditions and Severity of Acute COVID-19 Infection

All Pre-COVID comorbid conditions Severity of acute COVID-19 illness
(n=530) Cardio-pulmonary
(n=320)
Non-cardiopulmonary
(n=90)
None
(n=120)
Mechanical ventilation
(n=81)
No mechanical ventilation
(n=376)
Discharged from ED
(n=73)
Brain fog 20 (3.8%) 11 (3.4%) 1 (1.1%) 8 (6.7%) 3 (3.7%) 13 (3.5%) 4 (5.5%)
Cough 10 (1.9%) 6 (1.9%) 0 (0.0%) 4 (3.3%) 1 (1.2%) 7 (1.9%) 2 (2.7%)
Shortness of breath 55 (10.4%) 34 (10.6%) 9 (10.0%) 12 (10.0%) 10 (12.3%) 36 (9.6%) 9 (12.3%)
Neuropathy 27 (5.1%) 17 (5.3%) 7 (7.8%) 3 (2.5%) 17 (21.0%) 9 (2.4%) 1 (1.4%)
Headache 6 (1.1%) 4 (1.2%) 1 (1.1%) 1 (0.8%) 2 (2.5%) 4 (1.1%) 0 (0.0%)
Muscle aches 16 (3.0%) 9 (2.8%) 3 (3.3%) 4 (3.3%) 2 (2.5%) 12 (3.2%) 2 (2.7%)
Diarrhea 2 (0.4%) 2 (0.6%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 1 (0.3%) 1 (1.4%)
Chest pain 7 (1.3%) 5 (1.6%) 0 (0.0%) 2 (1.7%) 2 (2.5%) 3 (0.8%) 2 (2.7%)
Abdominal pain 2 (0.4%) 2 (0.6%) 0 (0.0%) 0 (0.0%) 1 (1.2%) 1 (0.3%) 0 (0.0%)
Loss of smell/taste 8 (1.5%) 5 (1.6%) 0 (0.0%) 3 (2.5%) 0 (0.0%) 6 (1.6%) 2 (2.7%)
Fatigue 29 (5.5%) 19 (5.9%) 3 (3.3%) 7 (5.8%) 3 (3.7%) 23 (6.1%) 3 (4.1%)
Other 47 (8.9%) 32 (10.0%) 6 (6.7%) 9 (7.5%) 13 (16.0%) 29 (7.7%) 5 (6.8%)