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. 2022 Jan 24;17(1):e0263080. doi: 10.1371/journal.pone.0263080

Fig 9. The effect of CDDO-Me (3 mg/kg) on gene expression.

Fig 9

CDDO-Me suppresses the expression of the NOX2 mRNA and increases SOD2 and catalase mRNA expression in the thoracic aorta of the WTD-GS (+) group. A-H: Quantitative PCR analysis of the expression of NQO1 (A), NOX2 (B), p47phox (C), SOD2 (D), catalase (E), TNFα (F), IL1β (G) and VCAM1 (H) mRNAs in the thoracic aorta. * P < 0.05, † P < 0.01, and ‡ P < 0.005, Bonferroni correction. The data are presented as the means ± SEM. N = 4 rats per group. CD, control diet; WTD, Western-type diet; GS, glucose spike.