Figure 8. S-gene codon pairs that display substantial evidence of coevolution within the BA.1 lineage since the divergence of sampled BA.1 sequences from their most recent common ancestor.

For SUBS = x,y,z: x = the number of non-synonymous substitutions likely occurring in the left codon along internal tree branches (i.e. where the mutant yielded multiple sampled and sequenced descendants): y = the number of non-synonymous substitutions likely occurring in the right codon along internal tree branches; and z = the number of non-synonymous substitutions likely occurring in both codons along the same internal tree branches. PP = posterior probability of conditional non-independence of substitutions at the two sites.