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. 2021 Dec 31;2021(12):CD003453. doi: 10.1002/14651858.CD003453.pub2

CTRI/2018/05/014220.

Methods Unknown
Participants Children with malocclusion requiring extraction of premolars for treatment
Inclusion criteria: patients reporting to the department for orthodontic treatment, no history of previous orthodontic treatment, crowding less than 5 mm, no other therapeutic intervention, no medical contraindications
Interventions Different methods of ligation: continuous bracket ligation technique versus conventional bracket ligation technique
17x25 inch stainless steel wire in situ for at least 6 weeks 
Outcomes Proclination and vertical changes in the position of the incisors, and mesial movement of the molars as measured on a lateral cephalogram and study models
Secondary: alleviation of crowding measured with Little's Index, arch length, chairside time needed for both the ligation techniques, changes in the Inter‐canine width and inter‐molar width, oral hygiene status ‐ Gingival Index and Plaque Index will be recorded 
Notes Emailed author; awaiting contact