Figure 2. Structure of the NgSAT hexamer.

A ribbon diagram of the overall structure of NgSAT shows that a dimer of trimers forms the hexameric unit through interactions between the N-terminal α-helical domains (A). Trimers form through interactions of the N-terminal α-helices (B) and left-handed β-helical C-terminal domain (C). The vertical dashed line represents the independent three-fold symmetry which is evident in (B) and (C). Sodium ions are shown as a purple spheres and l-malate is shown as yellow sticks. Asterisks shows active site extended loop. This figure was prepared with PyMOL.