Table 1.
Comparison of features between piRNAQuest V.2 and piRNAQuest
| Database content | piRNAQuest | piRNAQuest V.2 |
|---|---|---|
| Number of species | 3 | 28 |
| piRNA entries | 9,98,585 | 92,77,689 |
| Chromosomal distribution | Yes | Yes |
| Association with gene | Yes | Yes |
| Association with pseudogene | Yes | Yes |
| Association with repeat elements | Yes | Yes |
| Cluster information | Yes (Lau et al. method), for 3 species | Yes (Density based clustering approach), for 19 species |
| Association of clusters with genomic regions | Yes | Yes |
| Syntenic piRNA clusters | Yes | Yes |
| Ping-pong piRNAs | Yes | Yes |
| Ping-pong pattern Visualization | No | Yes |
| Tissue specific expression | Yes (Tissue type – 6, No. of Samples – 9) | Yes (Noraml Tissue type – 32, No. of Samples – 243) |
| piRNA disease association | No | Yes (16 types of cancer, 2 neurodegenerative diseases amd 3 other diseases) |
| Graphical representation of expression | No | Yes (For 32 normal tissue types and 16 types of cancer, 2 neurodegenerative diseases amd 3 other diseases) |
| Predicted piRNA – mRNA target pairs | No | Yes (For seven types of cancer, asthenozoospermia and mouse testis) |
| Predicted piRNA targets within lncRNAs | No | Yes (For seven types of cancers, asthenozoospermia and mouse testis) |
| piRNA target genes (literature curated) | No | Yes (for Human, Mouse and C. elegans) |
| Target prediction tool | No | Yes |
| Ping-pong overlap prediction tool | No | Yes |