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. 2021 Dec 14;19(1):1–11. doi: 10.1080/15476286.2021.2010959

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Differentially expressed 1018 miRNAs in COVID-19 patients with moderate-severe disease compared to healthy participants. (A) Principal component analysis (PCA) plot showing transcriptome differences between miRNA expression in COVID-19 patients compared to healthy participants. Each dot represents one of the total number of samples (12 samples from COVID-19 patients and 8 samples from healthy participants) used in the sequencing-based screening. (B) Heat map showing the expression of specific miRNAs in COVID-19 patients compared to healthy participants. The red and blue colours indicate up-regulation (log2 [2.5]) and down-regulation (log2 [−2.5]), respectively as shown in the colour bar.