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. 2021 Dec 14;19(1):1–11. doi: 10.1080/15476286.2021.2010959

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Pleiotropic effect of changes in the expression profiles of the circulating miRNAs in COVID-19 patients compared to healthy individuals. A schematic demonstrating the net effect of changes in circulating miRNA profiles in COVID-19 patients with moderate-severe disease when compared to healthy volunteers is presented. The direct published and confirmed targets of the miRNAs are ‘underlined’. The predicted targets of the miRNAs are highlighted in ‘yellow’ as there is no published data available as of this date. The red and blue arrows denote down-regulation or upregulation of miRNAs or the target genes, respectively.